I love my Manix 2 Cruwear, but IMO, the PM2 just can't be beat. However, I am right-handed, so I can't speak to the ease of use for lefties.
It is quite a bit different from the Manix, and like I said, they're both great. The S30V version is not that hard to find. The brown/S35VN Para is still around in some places for a little more than the standard version. The 204P and S90V Paras have gained the largest following, but they will be a premium to obtain.
If you can find a brown one, go for it! Even if all you can get is the S30V, it is still an amazing knife.