Right handed compression lock VS right handed frame lock. Once you teach yourself it just becomes second nature, either way. I've both of these beauties, I really couldn't choose one over the other, they are very different as well. Titanium VS CF. S30V/20cv VS LC200N. As far as opening the chef goes - I can fit the side of my thumb in the hole and use it that way, but I prefer to spydie flick it anywho. My hands are large and can still reliably open it either way.
Honestly they're both real nice pieces and I wouldn't want to choose between them, buuut I've been in the kaparas camp since day 1, I've bought the knife twice because of some sticky digits. I absolutely love it. Plus that contoured CF is luxury.