I managed to drop a closed compression lock folder (PM2) a few times and it opened as a result.
A compression lock is easy to shake open, so a shock introduced by a fall will open it, no problem. I tested the Para 3, the PM2, the Caribbean and the Sage.
OTOH, no matter how much wrist action I put into it, the Native can't be shaken open. The blade starts its travel, but the spring is plenty strong to move it back to its fully closed position immediately.
While closing the blade with a compression lock it is also unfortunately easy to drop the knife and that can be very dangerous. Major arteries in the thighs, damage to property etc.
In my case, this can happen especially with Taichung made Sage 5 for they keep the blade stuck in the open position. No matter how much strength I put in my pinch in an attempt to close the blade, it just stays open, while I'm desperately and repeatedly trying to flick it close. Simultaneously frustrating and dangerous. Not a way to operate a knife.
Another problem with the compression lock is the protruding tip of the finger choil as the Shaman is known for. I don't own a Shaman, but it is also a problem with the PM2. More often than not, the PM2 will fail to close after the choil bounces off of the tips of my index or middle fingers.
Here I am exposing the blade of my PM2 only by engaging the compression lock:

What is dangerous here is that there is no way to tell if the blade is seated properly or if it is still open, but to look at it, which is often impractical or impossible..
This is not an inherent issue with the compression lock itself, because this problem is not present on some models, like the Caribbean, the Sage 5 or the Para 3, but still, it shows that it can pop up with this type of lock in some sub-optimal designs.
Finally, I rate the compression lock as the least desirable in terms of ergonomics. It will create a hot spot in the hand web - a very delicate area.
TL;DR: the back-lock is way above the compression lock.