I've studied/dabbled in approx 10 martial arts, 5 of them Filipino knife arts and it all depends on how lucky I felt that day. There are a number of things that can be done.
IF you think that with no training you can stop an assailant armed with a knife, I suggest you go to the "Dog Brother's" website and buy "Die Another Day." It's very enlightening. Most of the attendees did not survive without quite a bit of training. They do show you the techniques to deal with an armed assailant, and they may work.
I'm pretty sure that I cannot run very far, although I've never tested myself, but I'd bet I run out of steam within a few blocks. Had open heart surgery in 2017 for a 3-way bypass and a new aortic valve, so my options may be different than yours. I might give him what he is looking for IF I have it, and hope he does not use his knife on me.
I might drop my wallet at his feet and as he bent over to pick it up, use my knife on his jugular.
I might take out my knife and confront him, mano-a-mano. But remember one thing. There are relatively few winners in knife fights, where fighters face off against each other. You may win. You may lose. Training might help you, but luck is really the thing that you would be looking to have at that moment. There is a discipline called Largo-Mano, and I know it well, but would I face off against a guy with a knife? Do I want to risk dying or being disfigured?
I'd probably drop the wallet at his feet and make my move, or just give him the wallet. And yes, I carry knives for self defense.
Spyderco Collection: Military (S110V), Bob Lum Darn Dao(CPM-154), Yojimbo 2 (1 in S30V & 2 in 20CV), Sustain(20CV), Native 5(Maxamet), Jumpmaster 2(H1), Province(4V). SHORT LIST: CF Shaman(S90V), Lum Tanto, Native Chief(?), Street Beat (AEB-L, NioMax or Nitro-V at 63HRC).