I really like the idea of a Caly-like blade and especially the Caly characteristic of having the blade as big as possible for the knife size. I too would like for it to be at least 3 3/8" closed or maybe even 3.5. I carried a small Gerber Easy-out about this size for years and it was plenty big for opening boxes, etc (though the handle was poorly designed - I removed a lot of unnecessary plastic from it, which also made it easier to open).
I would probably buy one with metal handles but would rather have G-10, maybe thinner than usual. I vote for a screwdriver tip like the one pictured, which can be used in both Phillips and flat blade screws. A serrated edge of some type would be more useful to me than the bottle opener -- almost everything has screw-off caps now... and I don't file my nails, but a file would be useful for other things.
Just brain storming, but wouldn't it be cool if it had a couple of torx sizes to use on your other knives